I bought the CityInkExpress CIS system a while ago for my Epson printer and it has been invaluable.
I love to see the Epson software hassling me to buy more ink then just resetting and continuing printing (I have the older setup, I understand that the newer ones even reset themselves so even less to do!) I don't print a great deal but it's lasted for three years!
Once it's set up there is nothing else to do, apart from keeping an eye on the ink level in the tanks, which do down very slowly.
It's well worth the initial outlay and has saved me a small fortune and should continue to do so.